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Food Biochemistry Division
 

Prof. Dr. Ir. Fransiska R. Zakaria, MSc

Academic Background

  • Undergraduate (Agriculture Product Technology, IPB-Indonesia)
  • MSc (Human Nutrition, Michigan State University- USA)
  • PhD (Medical Biology, University of Nancy I- France)

Email: zakaria@bgr.centrin.net.id

Areas of Expertise

  • Food and immune system (imunomodulator compund, antibody reaction and production)
  • Food Toxicology
  • Development of functional food

Teachings

  • Functional Food (Undergraduate Program)
  • Evaluation of Nutritional Value of Food Components (Undergraduate Program)
  • Evaluation Technique on Biological Value of Food Protein (Graduate Program)
  • Interaction of Food Nutrient (Graduate Program)
  • Food Toxicology (Graduate Program)
  • Immunology in Food (Graduate Program)
  • Food and Vascular System (Graduate Program)
  • Bioactive Compound of Food (Graduate Program)

Research Interests

  • Immunological respons and plasma free radical of population in Bogor exposed to street food contamination
  • Development of Health food drinks based on bean and vegetables fermented milks rich in vitamin B12
  • Mechanism of immunoenhancement and anticancer activity of ginger extracts
  • Production of Monoclonal Antibody of E coli O157
  • Identification of Small Scale Agroindustries Potential to Produce Infant Blended Food
  • Development of Small Scale Blended Food Agroindustry to Eliminate Malnutrition in Children
  • Development of Healthy Snack Products Based on Tempeh
  • Development of Natural Preservative and Health Food Ingredient Based on Traditional Starch Fermentation
  • The effect of feeding malt and mineral supplemented soyflour on the growth and protein body turn over of children under two year old and on mother perception toward nutrition
  • Screening of immunoenhancer activity in various part of Cincau plant to enrich the biological activity of the leaf gel
  • Production of cincau leaf based drinks

Selected Research Publications

  • Zakaria R Fransiska, Bus irwan, Siti M Pramudya, Sanjaya. 2000. Intervensi sayur dan buah pembawa vitamin C dan E meningkatkan sistem imun populasi buruh di Bogor. (Intervention with local fruits and vegetables carrying vitamin C and E improve the immune system of labours in Bogor Area). Bul Teknol dan Industri Pangan XI, 2, 21-17.
  • Zakaria-Rungkat F et al. 2000. Retinol accumulation in rat livers as a measure of carotenoid bioavailability of green vegetables and carbohydrate containing foods. J. Food Composition and Analysis, Vol 13 No 4.
  • Zakaria-Rungkat F. 2000. Scientific aspects of the impact of malnutrition occurred at under two year old on human resource development. Seminar on Generation Lost, Indonesian Food Technology Student Association, February 2000
  • Zakaria-Rungkat F ,. 2001. Pangan dan Pencegahan Kanker (Food and the Prevention of Cancer). Jurnal Teknologi dan Industri Pangan (Journal of Food Technology and Industry). Vol 12. No 2.
  • Zakaria-Rungkat F .2001. Khasiat berbagai pangan tradisional untuk pangan fungsional dan suplemen.(Effectiveness of Traditional Foods as Functional Foods and Supplements). National Seminar on Traditional Foods a Base of Functional Foods and Supplements). 14 Agustus, Jakarta.
  • Zakaria-Rungkat F . 2001. Effectiveness of Traditional Foods as Functional Foods and Supplements. In: Traditional Foods a Base of Functional Foods and Supplements (transl'ed) Eds. Dewanti, R & Nuraida L. PKMT, IPB, Bogor.
  • Zakaria-Rungkat F . 2001 Anticancer activity of green gel ( Cyclea barbata L Miers). traditional drink. . In : Traditional Foods a Base of Functional Foods and Supplements (transl'ed) (Eds. Dewanti, R & Nuraida L. PKMT, IPB, Bogor.
  • Zakaria-Rungkat F and Septelia A 2001 Antiartheriosclerosis of ginger extracts. In: Traditional Foods a Base of Functional Foods and Supplements (transl'ed). Eds. Dewanti, R & Nuraida L. PKMT, IPB, Bogor.
  • Didah N Faridah, Fransiska R Zakaria, Sri Budiarti. 2001. Aktifitas antialergi tipe I dari ekstrak air dan aseton jahe ( Zingiber officinale Roscoe ). (antiallergy activity of ginger extracts). In: Traditional Foods a Base of Functional Foods and Supplements (transl'ed) Eds. Dewanti, R & Nuraida L. PKMT, IPB, Bogor.
  • Zakaria-Rungkat F , Nurahman. 2001. BIOAVAILABILITY AND IMMUNE FUNCTIONALITY OF GINGER ( Zingiber officinale Roscoe ) WATER EXTRACT IN HEALTHY MALE STUDENT SUBJECTS. May, 2001. Bioavailability Symposium 2001, Interlaken, Switzerland.
  • Zakaria-Rungkat F & Septalia A. 2001. Ginger ( Zingiber officinale roscoe) extracts increase human LDL resistance to oxidation and prevent cholesterol accumulation in macrophage. The Second International Symposium on Natural Antioxidants: Molecular Mechanisms and Health Effects. June 4-8, Beijing China.
  • Zakaria-R F, Chalid SY, Setiawati R, Pranoto BA Wuyung EK and Kusmardi. 2002. Green gel leaf ( Cyclea barbata L Miers) powder improve lymphocyte and liver antioxidant and T cell cytotoxicity in tumour bearing mice. Second International Symposium on Antioxidants in Nutrition & Therapy: Mechanism in Physiology-Pathology-Pharmacology, 2-4 October, 2002. Kuta Debpasar, Bali, Indonesia.
  • Chalid SY, Wuyung EK, Zakaria-R F. 2002. Effects of Green c incau leaf ( Cyclea barbata L Miers) water extracts on liver antioxidant enzyme activities in mice transplanted with primary breast cancer cells. Second International Symposium on Antioxidants in Nutrition & Therapy: Mechanism in Physiology-Pathology-Pharmacology, 2-4 October, 2002. Kuta Debpasar, Bali, Indonesia.
  • Zakaria-R F, Nugrahenny D, Jacob A, Arisudana IG and Prangdimurti E. 2002. Water Extract of Green Gel Leaf ( Cyclea barbata L Miers) did not Induce Oxidation in Cytochrome but Increase Liver and Serum Antioxidant Activities in Rats. Second International Symposium on Antioxidants in Nutrition & Therapy: Mechanism in Physiology-Pathology-Pharmacology, 2-4 October, 2002. Kuta Debpasar, Bali, Indonesia.
  • Septiana AT, Muchtadi D, Fardiaz D, Zakaria R F , Sulistiyani. 2002. Aktivitas antioksidan ekstrak dikhlorometan dan air jahe (Z. officinalle Roscoe) pada asam linoleat. J Teknol&Inddustri Pangan, XIII (2): 105-110.
  • Zakaria-Rungkat F.et al. 2002 Utilization of fish surimi waste product for calf fetal serum subsitute in hybridoma cell culture 5 th JSPS International Seminar Marine Products Processing Technology, 19-20 Agustus 2002, Bogor, Indonesia.
  • Zakaria-Rungkat F. & Radiati LE. 2002. Inhibition of Salmonell a -FITC B toxin on hybridoma and caco cells by ginger extracts. Seminar of the Association of Microbiology Indonesia, 26 August, Bogor, Indonesia.
  • Zakaria-Rungkat F and Yuliarni. 2002. Isolation and testing of shrimp allergen protein for the preparation of allergy diagnostic allergen. 5 th JSPS International Seminar Marine Products Processing Technology..19-20 Agustus, Bogor, Indonesia.
  • Dwi B. Trisnoharjono, Fransisca R-Zakaria, Nazory Djazuli , Made Astawan. 2002. Changes of lysine availability in small size fish ( Sardinella fimbriata ) during salting, desalting and drying process to make fish flour. 5 th JSPS International Seminar Marine Products Processing Technology. 19-20 Agustus, Bogor , Indonesia.
  • Dwi B. Trisnoharjono, Fransisca R-Zakaria, Nazory Djazuli , Made Astawan 2002 Quality changes of small fish ( Sardinella Fimbriata ) during salting. 5 th JSPS International Seminar Marine Products Processing Technology, 19-20 Agustus, Bogor.
  • Zakaria-Rungkat F 2002a Significant impact of nutrient for cancer prevention and patients. DIGM Annual Meeting. Update on Multidisciplinary Management of Cancer 9-11 Agustus, Jakarta.
  • Zakaria-Rungkat F Budi Agus Pranoto, Kusmardi . 2002. Feeding powder and water extract of green c incau leaves in tumor bearing mice increase tumor necrotic and lymphocyte antioxidant capacity. DIGM Annual Meeting . Update on Multidisciplinary Management of Cancer. 9-11 Agustus. Jakarta.
  • Sri Yadial Chalid, Rosanti Setiawati, Puspita Eka Wuyung, Fransisca R. Zakaria . 2002. Lymphocyte proliferation and Tc cytotoxic capacity of mice fed powder and water extract of Green Cincau leaves and implemented with primary cancer cells . DIGM Annual Meeting . Update on Multidisciplinary Management of Cancer Jakarta, 9-11 Agustus.
  • Zakaria-Rungkat F. 2002. Possibility of Allergic Risks Induced by Genetically Modified Foods. Proceeding of Ecology and Health Safety Aspects of Genetically Modified Products. .Eds: Umboh, MIJ et al. Lemlit, UNIMA, Manado, Indonesia.
  • Zakaria-Rungkat F, 2002. Potential Allergic Reactions of Genetically Modified Foods. Int'l Seminar on “Ecology and Health Safety Aspects of Genetically Modified Agricultural Products. UNIBRAW, Malang, 19 May, 2002.
  • Zakaria-Rungkat F. 2002. Possibility of Allergic risk induced by foods derived from transgenic plants. International Seminar on Health Safety Aspects of Genetically Modified Food. Bogor, IPB, Indonesia, 23 May.
  • Zakaria-Rungkat F , Septalia A. 2002. Ginger ( Zingiber officinale Roscoe) drink did not lower human cholesterol but increase LDL resistance to oxidation. Seminar on Cardiology, From Basic to Clinical. Jakarta, 29-30 Juni 2002.
  • Zakaria-Rungkat F , Septalia A. 2002. Ginger Extracts are Capable in Preventing Cholesterol Accumulation in Macrophages. Seminar on Cardiology, From Basic to Clinical. Jakarta, 29-30 Juni 2002.
  • Rungkat-Zakaria, F., Heri Sutanto, Siti Madaniah-Pramudya and Sanjaya. 2002. Supplementation with local fruits and vegetables carrying vitamin A,C and E improved antioxidant status and effects of Pb toxicity in workers in Bogor. National Seminar on Recent Isuues in Food Safety. Srikandi Foundation, IPB, Bogor , Indonesia.
  • Zakaria-Rungkat F , Koesitoresmi A, Palupi N. 2002. Leaf and stalk water extracts of Cyclea barbata L Miers have antioxidant activity and non toxic to human lymphocyte cells. National Seminar on Recent Isuues in Food Safety. Srikandi Foundation, IPB, Bogor, Indonesia.
  • Zakaria-Rungkat, F., Nurahman, Prangdimurti, E., Tejasari. 2003. Antioxidant and Immunoenhancement Activities of Ginger ( Zingiber officinale Roscoe) Extracts and Compounds in In Vitro and In Vivo Mouse and Human System. Nutraceuticals and Foods.8; 96-104.
  • Damayanthi E, Muchtadi D, Syarif H, Rungkat-Zakaria F Wijaya CH, Darmadji DS. 2003. Pengaruh derajat sosoh terhadap kandungan gizi, serat pangan dan oryzanol bekatul padi ( Oryza sativa ) awet. Media Gizi dan Keluarga, 27:104-114.
  • Fransiska Zakaria. 2004. Kajian Keamanan Perisa. Seminar Sehari. Penggunaan Bahan Tambahan Perisa dalam Produk Pangan. Direktorat Standardisasi Produk Pangan, Badan Pengawas Obat dan Makanan. Hotel Borobudur, Jakarta 21 Desember 2004.
  • Fransiska Rungkat-Zakaria , Wanchai Worawattanamateekul, Ong-ard Lawhavini. 2004. SUBSTITUTION OF FETAL BOVINE SERUM IN HYBRIDOMA CELL CULTURES BY FISH SERUM OBTAINED FROM SURIMI WASTE PRODUCTS . SEARCA Bull. Phillipines, In progress.
  • Fransiska Rungkat-Zakaria , Wanchai Worawattanamateekul, Ong-ard Lawhavinit . 2004. SUBSTITUTION OF FETAL BOVINE SERUM IN LYMPHOCYTE CELL CULTURES BY FISH SERUM PREPARED FROM INDUSTRIAL SURIMI WASTE PRODUCTS. SEARCA Bull. Phillipines In Progress.
  • Winarsi H, Muchtadi D, Rungkat-Zakaria F , Purwantara B. 2004. Respons hormonal-imunitas wanita premenopos yang diintervensi miniman fungsional berbasis susu skim yang disuplementasi dengan 100 mg isoflavon kedelai dan 8 mg Zn-zulfat (susumeno). J Teknol Ind Pangan. 1:28-34.
  • Damayanthi E, Muchtadi D, Rungkat-Zakaria F , syarif H, Wijaya CH, Darmadji DS. 2004. Aktivitas antioksidan minyak bekatul padi awet dan fraksinya secara in vitro (in vitro antioxidant activity of stabilized rice bran and its fraction). J Teknol Ind Pangan. 1:11-19.
  • Hermawati D, Sudarwanto M, Soekarto ST, Rungkat-Zakaria F , Sudardjat S, Tjatur R FS. 2004. Aktivitas antimikroba susu kuda Sumbawa (antimicrobial activity of the Sumbawa Mare milk). J Teknol Ind Pangan. 1:47-53.
  • Fransiska R-Zakaria. 2004. Evaluasi Keamanan Konsumsi Oksigen dari Air Minum Beroksigen bagi Kesehatan. Materi Presentasi Diskusi Ilmiah air minum Penambah Oksigen. 18 September 2004, Departemen Teknologi Pangan dan Gizi, Fak Teknolog pertanian, IPB, Bogor dan R&K Healthy Living, Bandung.
  • Aquarini TH, Rungkat-Zakaria F , Suhartono MT, Nurfaridah D. 2005. Kumis kucing (Orthosiphon stamineus Benth) leaf and knop (Gomphrena globosa L) flower extracts are not toxic to human lymphocyte cells in vitro. „Chemicals, Human & Environment”, The SSCT-ETS 2005 Conference, Toila, Estonia. (Publication in process).
  • Fransiska R-Zakaria, Ilyas E. 2005. Safety and benefit evaluation of oxygenated water as a functional drink in rats and human subjects. Abstract Book. The 1st Congress of the Working Group on Metabolism and Clinical Nutrition. Optimizing Strategy In Clinical Nutrition In Health and Diseases. Gran Melia Hotel, Jakarta 15-17 April 2005.
  • Fransiska R-Zakaria, Fiona P. Koestomo, Nuni Novitasari and Ingrid S. Surono. 2005. Potential of Lactic Bacteria IS-27526 Isolated from Dadih in Increasing IgA Antibody Secretion in Children Below Five Year Old. Proceeding. International Symposium on International Symposium Probiotic for Human and Immunity, September 7-8, 2004; Pelangi Hotel, Seminyak, Bali.
  • Ingrid S. Surono 1 , Fransiska R-Zakaria 2 , Nuni Novitasari 3 , and Fiona P. Koestomo 3. 2005. Changes in Nutritional Status and Total serum IgG Secretion of Under Five-Year Old Children after Receiving Low Fat Milk Supplemented Probiotic Dadih Lactic Acid Bacteria. Proceeding.
  • Winarsi H, Muchtadi D, Zakaria FR , Purwanto.2005. Kajian tentang wanita perimenopause di Purwokerto dan beberapa permasalahan dalam sistem imunnya. Obstet Ginekol Indonesia, 29,3, 177-83.
  • Rungkat-Zakaria, F. 2006. ZAT ADITIF DAN PENGARUHNYA TERHADAP METABOLISME TUBUH MANUSIA. Pelatihan pengolahan produk Hortikultura, Poltan Payakumbuh, Bukittinggi 9-11 Juni.
  • Rungkat-Zakaria, F. 2006. REKAYASA PROSES PENGOLAHAN HASIL-HASIL HORTIKULTURA. Pelatihan pengolahan produk Hortikultura, Poltan Payakumbuh, Bukittinggi 9-11 Juni.

Personal Profile

  • Member of Indonesian Association of Food Technologists (PATPI)
 
(C) 2005 Department of Food Science and Technology, IPB